Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - Nucleoside Antimetabolite/Analog - Metesind glucuronate

Metesind glucuronate

CAS No. 157182-23-5

Metesind glucuronate( AG 331 | AG-265 glucuronate )

Catalog No. M12243 CAS No. 157182-23-5

Metesind glucuronate (AG 331;AG-265 glucuronate) is a potent thymidylate synthase (TS) inhibitor with IC50/IC90 of 0.7/3.0 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 963 Get Quote
50MG 1962 Get Quote
100MG 2520 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Metesind glucuronate
  • Note
    Research use only, not for human use.
  • Brief Description
    Metesind glucuronate (AG 331;AG-265 glucuronate) is a potent thymidylate synthase (TS) inhibitor with IC50/IC90 of 0.7/3.0 uM.
  • Description
    Metesind glucuronate (AG 331;AG-265 glucuronate) is a potent thymidylate synthase (TS) inhibitor with IC50/IC90 of 0.7/3.0 uM; inhibits the cofactor binding site of TS, and accumulates in the S phase of the cell cycle in H35 cells at 10 uM.Brain Cancer Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AG 331 | AG-265 glucuronate
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Nucleoside Antimetabolite/Analog
  • Recptor
    Nucleoside Antimetabolite/Analog
  • Research Area
    Cancer
  • Indication
    Brain Cancer

Chemical Information

  • CAS Number
    157182-23-5
  • Formula Weight
    630.679
  • Molecular Formula
    C23H24N4O3SC6.H10O7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=S(N1CCOCC1)(C2=CC=C(CN(C3=CC=C4N=C(N)C5=CC=CC3=C54)C)C=C2)=O.O=C[C@@H]([C@H]([C@@H]([C@@H](C(O)=O)O)O)O)O
  • Chemical Name
    6-[N-Methyl-N-[4-(morpholinosulfonyl)benzyl]amino]benz[cd]indol-2(1H)-imine glucuronate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pressacco J, et al. Cancer Res. 1995 Apr 1;55(7):1505-8. 2. O'Connor BM, et al. Cancer Chemother Pharmacol. 1994;34(3):225-9. 3. Panadero A, et al. Oncol Res. 1995;7(2):73-81.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Triapine

    Triapine (3-AP, PAN-811, OCX191, NSC 663249) is a potent ribonucleotide reductase inhibitor with broad spectrum antitumor activity.

  • 5-Azacytidine

    A chemical analog of Cytidine that inhibits DNA methyltransferase; induces mitochondrial apoptosis and autophagy.

  • 3-Methylcytidine

    3-Methylcytidine as biomarkers of four different types of cancer: lung cancer gastric cancer colon cancer and breast cancer.

Sign In Join Free